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The emergence of multidrug-resistant Mycobacterium tuberculosis (MTB) and the close association of MTB with HIV accentuates the need for simple, rapid and affordable methods of anti-TB susceptibility testing, especially in resource constrained settings.
The resazurin microtitreplate assay (REMA) is an innovative colorimetric assay using redox indicator salts to detect MTB cell growth and viability in a week.
Researchers from the Department of Medical Microbiology, National Health Laboratory Services and the University of Kwa-Zulu Natal in Durban, South Africa, have assessed the performance of the REMA assay against the gold standard DST (drug susceptibility testing) method in a high TB burden reference laboratory.
You can download a poster about the study in PDF format by clicking on the link in the top right corner of this page.