Ebola: Response, sequencing, vaccines and survivors

The European Mobile Laboratory, EMLab, was the first EBOV diagnostics unit deployed to the outbreak epicentre by WHO in March 2014.

Special issue on strengthening tuberculosis diagnostic networks in Africa

Call for Papers: Special issue on strengthening tuberculosis diagnostic networks in Africa - African Journal of Laboratory Medicine

Malaria – Are males more sensitive than females?

ASLM: Ensuring High Quality Point-of-Care Testing

East African Leaders Join Together to Develop Country-Specific Plans for Point-of-Care Testing.

ASLM: Antimicrobial resistance, an International Priority

Two great articles from the African Society for Laboratory Medicine looking at the increasing risk posed by antimicrobial resistance.

ASLM: Reconstructing Laboratory Systems: How to Rebuild in Ebola-Affected Countries

ASLM: Using a Score Card to Assess Lab Functionality

New articles from the African Society for Laboratory Medicine (ASLM).

The Federation of Infectious Diseases Societies of Southern Africa (FIDSSA) Quarterly Journal

Using parasite population genetics to understand transmission dynamics in NTDs

Schistosomiasis, is a chronic, debilitating disease. Uganda began a National Control Programme in 2003 with annual MDA of praziquantel. MDA on this scale provides strong selective pressures on the parasite population with an associated risk of drug resistance developing.

Development of Leishmania vaccines in the era of visceral leishmaniasis elimination

Chronic hepatitis B infection in sub-Saharan Africa: a grave challenge and a great hope

The challenges facing malaria research

In this video, Professor Theonest Mutabingwa discusses the two key challenges that face developing countries to progress their malaria research.

Responding to the challenge of antimalarial drug resistance

In this video of a seminar delivered at the University of Oxford in June 2014, Professor Nicholas White talks about the challenge of antimalarial resistance.

The major obstacle of malaria drug efficacy

Anders Björkman is Professor of Infectious Disease at the Karolinska Institute. In this video, Anders talks about how the efficacy of antimalarials is a major obstacle in the path towards full malaria elimination.

Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

Vaccines for Malaria and Ebola, Weatherall lecture 2015

In this lecture Professor Adrian Hill talks about the latest advances in the development of vaccines for Malaria and Ebola.

Infectious diseases and Microbiology videos

Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain

Immunity to Malaria in Humans

In this seminar Professor Kevin Marsh describes how knowledge of immunity to malaria in humans has developed over the past thirty years and what impact this has for future research.

Ebola Virus Entry: A Curious and Complex Series of Events

ABRAID – The Atlas of Baseline Risk Assessment for Infectious Diseases - Call for feedback

ABRAID, new website of infectious diseases risk maps 

The Ebola Outbreak - Possible Implications that Media Reporting may Have -

Pioneering New Diagnostics: Addressing Challenges and Implications for Point-of-Care Testing in African Settings

Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury

A Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infections

A Stronger Post-Publication Culture Is Needed for Better Science

UNICEF Cholera Toolkit

HIV/AIDS diagnostics technology landscape

Hepatitis C diagnostics technology landscape

Epidemics and vaccines videos

Early Virus-Host Interactions Dictate the Course of a Persistent Infection

Effects of introducing Xpert MTB/RIF test on multi-drug resistant tuberculosis diagnosis in KwaZulu-Natal South Africa

New PLOS collections on NTDs and Co-infections

Clinical Immunology Collection from PLOS and PLOS Pathogens Pearls

Rapid and Inexpensive Detection of MDR Mycobacterium tuberculosis using a Resazurin Microtitreplate Assay in a High Burden Tuberculosis Reference Laboratory

Proficiency Testing: Diagnosing Threats to Quality

The Clinical and Economic Impact of Point-of-Care CD4 Testing in Mozambique and Other Resource-Limited Settings: A Cost-Effectiveness Analysis.

Aging and HIV/AIDS: pathogenetic role of therapeutic side effects

Candida albicans Pathogenicity and Epithelial Immunity

The Ebola Virus Epidemic - where to from here...

The Ebola virus epidemic may well spread out of Africa. Dr Greg Martin takes a look at some of the variables that contribute to this risk and discusses some steps that should be taken.

Community-Based Interventions for the Prevention and Control of Infectious Diseases of Poverty

This thematic series of eight papers provides an overview on infectious diseases of poverty and integrated community-based interventions, describes the analytical framework and the methodology used to guide the systematic reviews, reports findings for the effectiveness of community-based interventions for the prevention and control of helminthic NTDs, non-helminthic NTDs, malaria, HIV/AIDS and tuberculosis and proposes a way forward. While previous reviews focus on process and effectiveness of integrated community-based interventions under real life field conditions, this series of papers evaluates the efficacy of such interventions with respect to disease or prevention outcomes.

An Integrated Lab-on-Chip for Rapid Identification and Simultaneous Differentiation of Tropical Pathogens

Aeromonas Infections

Antimicrobial Stewardship and Surveillance: Great Expectations

The attached article, published in Emergency Medicine Volume 3 Issue 6, discusses the frequent use of antimicrobials in the critically ill which has led to the rise in multidrug resistant organisms.

Microbiology Clinical Laboratory SOPs

New publication on rifampicin Mono-Resistance in TB

Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood in Lymphocytes in Patients in Dhaka, Bangladesh

Clinical Research Laboratories for Trials in Global Health in Central Africa

The authors present the story of building a succesful research laboratory in Cameroon, including how they managed building up the infrastructure, equipment maintenance, staff training.

Creepy Dreadful Wonderful Parasites

Fantastic parasitology blog

Serious and Life-Threatening Pregnancy-Related Infections: Opportunities to Reduce the Global Burden

This Policy Forum article aims to highlight opportunities for screening and appropriate treatment of life-threatening pregnancy-related interventions.

Bug Challenge Number 2

Streptococcal Pharyngitis - 2012 IDSA Guidelines

Point of Care Testing for Infectious Diseases: Diversity, Complexity and Barriers in Low- and Middle Income Countries

The Future of Diagnostic Microbiology – whole genome sequencing?

Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

Diagnosis of visceral leishmaniasis

Enteric fever diagnostics reviews

Mobile Phone Based Clinical Microscopy for Global Health Applications

Web-Based Virtual Microscopy for Parasitology: A Novel Tool for Education and Quality Assurance

Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysis

Tuberculosis Diagnostic Technology Landscape

Alternative methods of diagnosing drug resistance - What can they do for me?

Point-of-Care Tests to Strengthen Health Systems and Save Newborn Lives: The Case of Syphilis

Diagnostic Accuracy of Molecular Amplification Tests for Human African Trypanosomiasis—Systematic Review

Towards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis

Nucleic acid amplification testing for Neisseria gonorrhoeae: an ongoing challenge

Indian Bacterial Surveillance Study Shows High Number of Resistant Bacteria - Article of the Month, June 2012

  June’s article of the month features a paper from Infection and Drug Resistance called “High prevalence of extended-spectrum β-lactamase-producing pathogens: results of a surveillance study in two hospitals in Ujjain, India”.

Bug Challenge

Our first "Bug Challenge" comes from Mahosot Hospital, Vientiane, Laos

Pneumonia Etiology Research for Child Health - Article of the Month, May 2012

May's article of the month features a supplement from Clinical Infectious Diseases on "Pneumonia Etiology Research for Clinical Health"

Rapid Syphilis Test Toolkit

Diagnostics to Reduce the Global Burden of Disease