The European Mobile Laboratory, EMLab, was the first EBOV diagnostics unit deployed to the outbreak epicentre by WHO in March 2014.
Call for Papers: Special issue on strengthening tuberculosis diagnostic networks in Africa - African Journal of Laboratory Medicine
East African Leaders Join Together to Develop Country-Specific Plans for Point-of-Care Testing.
Two great articles from the African Society for Laboratory Medicine looking at the increasing risk posed by antimicrobial resistance.
ASLM: Reconstructing Laboratory Systems: How to Rebuild in Ebola-Affected Countries
by The Editorial TeamNew articles from the African Society for Laboratory Medicine (ASLM).
The Federation of Infectious Diseases Societies of Southern Africa (FIDSSA) Quarterly Journal
by Karla LamUsing parasite population genetics to understand transmission dynamics in NTDs
by The Editorial TeamSchistosomiasis, is a chronic, debilitating disease. Uganda began a National Control Programme in 2003 with annual MDA of praziquantel. MDA on this scale provides strong selective pressures on the parasite population with an associated risk of drug resistance developing.
Development of Leishmania vaccines in the era of visceral leishmaniasis elimination
by Christian R. Engwerdaa and Greg MatlashewskibChronic hepatitis B infection in sub-Saharan Africa: a grave challenge and a great hope
by Alexander J. Stockdale and Anna Maria GerettiIn this video, Professor Theonest Mutabingwa discusses the two key challenges that face developing countries to progress their malaria research.
In this video of a seminar delivered at the University of Oxford in June 2014, Professor Nicholas White talks about the challenge of antimalarial resistance.
Anders Björkman is Professor of Infectious Disease at the Karolinska Institute. In this video, Anders talks about how the efficacy of antimalarials is a major obstacle in the path towards full malaria elimination.
Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance
by Mahima Swamy et alIn this lecture Professor Adrian Hill talks about the latest advances in the development of vaccines for Malaria and Ebola.
Infectious diseases and Microbiology videos
by Nuffield Department of MedicineFour decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain
by Vegard Eldholm et alIn this seminar Professor Kevin Marsh describes how knowledge of immunity to malaria in humans has developed over the past thirty years and what impact this has for future research.
Ebola Virus Entry: A Curious and Complex Series of Events
by Sven Moller-Tank, Wendy MauryABRAID – The Atlas of Baseline Risk Assessment for Infectious Diseases - Call for feedback
by Dr Catherine MoyesABRAID, new website of infectious diseases risk maps
The Ebola Outbreak - Possible Implications that Media Reporting may Have -
by Cecaro M and Ramsamy YPioneering New Diagnostics: Addressing Challenges and Implications for Point-of-Care Testing in African Settings
by Laurel OldachNeutrophils: Between Host Defence, Immune Modulation, and Tissue Injury
by Philipp Kruger et alA Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infections
by Kfir Oved, et alA Stronger Post-Publication Culture Is Needed for Better Science
by Hilda BastianUNICEF Cholera Toolkit
by UNICEFHIV/AIDS diagnostics technology landscape
by UnitaidHepatitis C diagnostics technology landscape
by UnitaidEarly Virus-Host Interactions Dictate the Course of a Persistent Infection
by Brian M. Sullivan, John R. Teijaro, Juan Carlos de la Torre, Michael B. A. OldstoneEffects of introducing Xpert MTB/RIF test on multi-drug resistant tuberculosis diagnosis in KwaZulu-Natal South Africa
by Nomonde R Dlamini-Mvelase, Lise Werner, Rogerio Phili, Lindiwe P Cele and Koleka P MlisanaRapid and Inexpensive Detection of MDR Mycobacterium tuberculosis using a Resazurin Microtitreplate Assay in a High Burden Tuberculosis Reference Laboratory
by Prenika Jaglal, Melendhran Pillay, Koleka MlisanaProficiency Testing: Diagnosing Threats to Quality
by Laurel Oldach et alThe Clinical and Economic Impact of Point-of-Care CD4 Testing in Mozambique and Other Resource-Limited Settings: A Cost-Effectiveness Analysis.
by Emily P. Hyle et al.Aging and HIV/AIDS: pathogenetic role of therapeutic side effects
by Rebecca A Torres and William LewisCandida albicans Pathogenicity and Epithelial Immunity
by Naglik JR, Richardson JP, Moyes DLThe Ebola virus epidemic may well spread out of Africa. Dr Greg Martin takes a look at some of the variables that contribute to this risk and discusses some steps that should be taken.
Community-Based Interventions for the Prevention and Control of Infectious Diseases of Poverty
by Rehana A SalamThis thematic series of eight papers provides an overview on infectious diseases of poverty and integrated community-based interventions, describes the analytical framework and the methodology used to guide the systematic reviews, reports findings for the effectiveness of community-based interventions for the prevention and control of helminthic NTDs, non-helminthic NTDs, malaria, HIV/AIDS and tuberculosis and proposes a way forward. While previous reviews focus on process and effectiveness of integrated community-based interventions under real life field conditions, this series of papers evaluates the efficacy of such interventions with respect to disease or prevention outcomes.
An Integrated Lab-on-Chip for Rapid Identification and Simultaneous Differentiation of Tropical Pathogens
by Jeslin J. L. Tan, Monica Capozzoli, et alThe attached article, published in Emergency Medicine Volume 3 Issue 6, discusses the frequent use of antimicrobials in the critically ill which has led to the rise in multidrug resistant organisms.
New publication on rifampicin Mono-Resistance in TB
by Yacoob Mahomed Coovadia, Sharana Mahomed, Melendhran Pillay, Lise Werner, Koleka MlisanaEvaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood in Lymphocytes in Patients in Dhaka, Bangladesh
by Farhana Khanam, Alaullah Sheikh, Abu Sayeed, Saraur Bhuiyan, Feroza Kaneez Choudhury, Umme Salma, Shahnaz Pervin, Tania Sultana, Dilruba Ahmed, Doli Goswami, Lokman Hossain, KZ Mamun, Richell C Charles, W. Abdullah Brooks, Stephen B. Calderwood, Alejandro Cravioto, Edward T Ryan, Firdausi QadriClinical Research Laboratories for Trials in Global Health in Central Africa
by ALI Innocent, akindeh, Prof Wilfred F. MbachamThe authors present the story of building a succesful research laboratory in Cameroon, including how they managed building up the infrastructure, equipment maintenance, staff training.
Creepy Dreadful Wonderful Parasites
by "Parasitology Gal"Fantastic parasitology blog
Serious and Life-Threatening Pregnancy-Related Infections: Opportunities to Reduce the Global Burden
by Courtney A. GravettThis Policy Forum article aims to highlight opportunities for screening and appropriate treatment of life-threatening pregnancy-related interventions.
Streptococcal Pharyngitis - 2012 IDSA Guidelines
by Stanford T. Shulman, Alan L. Bisno, Herbert W. Clegg, Michael A. Gerber, Edward L. Kaplan, Grace Lee, Judith M. Martin, Chris Van BenedenPoint of Care Testing for Infectious Diseases: Diversity, Complexity and Barriers in Low- and Middle Income Countries
by Nitika Pant Pai, MD MPH PhD, Caroline Vadnais, Claudia Denkinger, Nora Engel, Madhu PaiThe Future of Diagnostic Microbiology – whole genome sequencing?
by Susanna DunachieVisceral leishmaniasis: what are the needs for diagnosis, treatment and control?
by François Chappuis, Shyam Sundar, Asrat Hailu, Hashim Ghalib, Suman Rijal, Rosanna W. PeelingDiagnosis of visceral leishmaniasis
by Pankaj Srivastava, Anand Dayama, Sanjana Mehrotra, Shyam SundarEnteric fever diagnostics reviews
by Paula Bianca BlomquistMobile Phone Based Clinical Microscopy for Global Health Applications
by David N. Breslauer, Robi N. Maamari, Neil A. Switz, Wilbur A. Lam, Daniel A. FletcherWeb-Based Virtual Microscopy for Parasitology: A Novel Tool for Education and Quality Assurance
by Ewert Linder, Mikael Lundin, Cecilia Thors, Marianne Lebbad, Jadwiga Winiecka-Krusnell, Heikki Helin, Byron Leiva, Jorma Isola, Johan LundinDirect susceptibility testing for multi drug resistant tuberculosis: a meta-analysis
by Freddie Bwanga, Sven Hoffner, Melles Haile, Moses L JolobaAlternative methods of diagnosing drug resistance - What can they do for me?
by David AJ Moore, N Sarita ShahPoint-of-Care Tests to Strengthen Health Systems and Save Newborn Lives: The Case of Syphilis
by David Mabey, Kimberly Sollis, Helen Kelly, Adele Schwartz Benzaken, Edward Bitarakwate, John Changalucha, Xiang-Sheng Chen, Yue-Pin Ying, Patricia Garcia, Susan Strasser, Namwinga Chintu, Tikki Pang, Fern Terris-Prestholt, Sedona Sweeney, Rosanna PeelingDiagnostic Accuracy of Molecular Amplification Tests for Human African Trypanosomiasis—Systematic Review
by Claire M. Mugasa, Emily R. Adams, Kimberly R. Boer, Heleen C. Dyserinck, Philippe BüscherTowards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis
by Enock Matovu, Anne Juliet Kazibwe, Claire Mack Mugasa, Joseph Mathu Ndungu, Zablon KithingiNucleic acid amplification testing for Neisseria gonorrhoeae: an ongoing challenge
by David M Whiley, John W Tapsall, Theo P SlootsJune’s article of the month features a paper from Infection and Drug Resistance called “High prevalence of extended-spectrum β-lactamase-producing pathogens: results of a surveillance study in two hospitals in Ujjain, India”.
Bug Challenge
by EditorsOur first "Bug Challenge" comes from Mahosot Hospital, Vientiane, Laos
May's article of the month features a supplement from Clinical Infectious Diseases on "Pneumonia Etiology Research for Clinical Health"