The European Mobile Laboratory, EMLab, was the first EBOV diagnostics unit deployed to the outbreak epicentre by WHO in March 2014.
Call for Papers: Special issue on strengthening tuberculosis diagnostic networks in Africa - African Journal of Laboratory Medicine
East African Leaders Join Together to Develop Country-Specific Plans for Point-of-Care Testing.
Two great articles from the African Society for Laboratory Medicine looking at the increasing risk posed by antimicrobial resistance.
ASLM: Reconstructing Laboratory Systems: How to Rebuild in Ebola-Affected Countriesby The Editorial Team
New articles from the African Society for Laboratory Medicine (ASLM).
The Federation of Infectious Diseases Societies of Southern Africa (FIDSSA) Quarterly Journalby Karla Lam
Using parasite population genetics to understand transmission dynamics in NTDsby The Editorial Team
Schistosomiasis, is a chronic, debilitating disease. Uganda began a National Control Programme in 2003 with annual MDA of praziquantel. MDA on this scale provides strong selective pressures on the parasite population with an associated risk of drug resistance developing.
Development of Leishmania vaccines in the era of visceral leishmaniasis eliminationby Christian R. Engwerdaa and Greg Matlashewskib
Chronic hepatitis B infection in sub-Saharan Africa: a grave challenge and a great hopeby Alexander J. Stockdale and Anna Maria Geretti
In this video, Professor Theonest Mutabingwa discusses the two key challenges that face developing countries to progress their malaria research.
In this video of a seminar delivered at the University of Oxford in June 2014, Professor Nicholas White talks about the challenge of antimalarial resistance.
Anders Björkman is Professor of Infectious Disease at the Karolinska Institute. In this video, Anders talks about how the efficacy of antimalarials is a major obstacle in the path towards full malaria elimination.
Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistanceby Mahima Swamy et al
In this lecture Professor Adrian Hill talks about the latest advances in the development of vaccines for Malaria and Ebola.
Infectious diseases and Microbiology videosby Nuffield Department of Medicine
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strainby Vegard Eldholm et al
In this seminar Professor Kevin Marsh describes how knowledge of immunity to malaria in humans has developed over the past thirty years and what impact this has for future research.
Ebola Virus Entry: A Curious and Complex Series of Eventsby Sven Moller-Tank, Wendy Maury
ABRAID – The Atlas of Baseline Risk Assessment for Infectious Diseases - Call for feedbackby Dr Catherine Moyes
ABRAID, new website of infectious diseases risk maps
The Ebola Outbreak - Possible Implications that Media Reporting may Have -by Cecaro M and Ramsamy Y
Pioneering New Diagnostics: Addressing Challenges and Implications for Point-of-Care Testing in African Settingsby Laurel Oldach
Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injuryby Philipp Kruger et al
A Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infectionsby Kfir Oved, et al
A Stronger Post-Publication Culture Is Needed for Better Scienceby Hilda Bastian
UNICEF Cholera Toolkitby UNICEF
HIV/AIDS diagnostics technology landscapeby Unitaid
Hepatitis C diagnostics technology landscapeby Unitaid
Early Virus-Host Interactions Dictate the Course of a Persistent Infectionby Brian M. Sullivan, John R. Teijaro, Juan Carlos de la Torre, Michael B. A. Oldstone
Effects of introducing Xpert MTB/RIF test on multi-drug resistant tuberculosis diagnosis in KwaZulu-Natal South Africaby Nomonde R Dlamini-Mvelase, Lise Werner, Rogerio Phili, Lindiwe P Cele and Koleka P Mlisana
Rapid and Inexpensive Detection of MDR Mycobacterium tuberculosis using a Resazurin Microtitreplate Assay in a High Burden Tuberculosis Reference Laboratoryby Prenika Jaglal, Melendhran Pillay, Koleka Mlisana
Proficiency Testing: Diagnosing Threats to Qualityby Laurel Oldach et al
The Clinical and Economic Impact of Point-of-Care CD4 Testing in Mozambique and Other Resource-Limited Settings: A Cost-Effectiveness Analysis.by Emily P. Hyle et al.
Aging and HIV/AIDS: pathogenetic role of therapeutic side effectsby Rebecca A Torres and William Lewis
Candida albicans Pathogenicity and Epithelial Immunityby Naglik JR, Richardson JP, Moyes DL
The Ebola virus epidemic may well spread out of Africa. Dr Greg Martin takes a look at some of the variables that contribute to this risk and discusses some steps that should be taken.
Community-Based Interventions for the Prevention and Control of Infectious Diseases of Povertyby Rehana A Salam
This thematic series of eight papers provides an overview on infectious diseases of poverty and integrated community-based interventions, describes the analytical framework and the methodology used to guide the systematic reviews, reports findings for the effectiveness of community-based interventions for the prevention and control of helminthic NTDs, non-helminthic NTDs, malaria, HIV/AIDS and tuberculosis and proposes a way forward. While previous reviews focus on process and effectiveness of integrated community-based interventions under real life field conditions, this series of papers evaluates the efficacy of such interventions with respect to disease or prevention outcomes.
An Integrated Lab-on-Chip for Rapid Identification and Simultaneous Differentiation of Tropical Pathogensby Jeslin J. L. Tan, Monica Capozzoli, et al
Aeromonas Infectionsby yogandree, Y Mahabeer, Koleka Mlisana
The attached article, published in Emergency Medicine Volume 3 Issue 6, discusses the frequent use of antimicrobials in the critically ill which has led to the rise in multidrug resistant organisms.
New publication on rifampicin Mono-Resistance in TBby Yacoob Mahomed Coovadia, Sharana Mahomed, Melendhran Pillay, Lise Werner, Koleka Mlisana
Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood in Lymphocytes in Patients in Dhaka, Bangladeshby Farhana Khanam, Alaullah Sheikh, Abu Sayeed, Saraur Bhuiyan, Feroza Kaneez Choudhury, Umme Salma, Shahnaz Pervin, Tania Sultana, Dilruba Ahmed, Doli Goswami, Lokman Hossain, KZ Mamun, Richell C Charles, W. Abdullah Brooks, Stephen B. Calderwood, Alejandro Cravioto, Edward T Ryan, Firdausi Qadri
Clinical Research Laboratories for Trials in Global Health in Central Africaby ALI Innocent, akindeh, Prof Wilfred F. Mbacham
The authors present the story of building a succesful research laboratory in Cameroon, including how they managed building up the infrastructure, equipment maintenance, staff training.
Creepy Dreadful Wonderful Parasitesby "Parasitology Gal"
Fantastic parasitology blog
Serious and Life-Threatening Pregnancy-Related Infections: Opportunities to Reduce the Global Burdenby Courtney A. Gravett
This Policy Forum article aims to highlight opportunities for screening and appropriate treatment of life-threatening pregnancy-related interventions.
Bug Challenge Number 2by David Dance, Sayapeth Rattanavong, Viengmon Davong
Streptococcal Pharyngitis - 2012 IDSA Guidelinesby Stanford T. Shulman, Alan L. Bisno, Herbert W. Clegg, Michael A. Gerber, Edward L. Kaplan, Grace Lee, Judith M. Martin, Chris Van Beneden
Point of Care Testing for Infectious Diseases: Diversity, Complexity and Barriers in Low- and Middle Income Countriesby Nitika Pant Pai, MD MPH PhD, Caroline Vadnais, Claudia Denkinger, Nora Engel, Madhu Pai
The Future of Diagnostic Microbiology – whole genome sequencing?by Susanna Dunachie
Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?by François Chappuis, Shyam Sundar, Asrat Hailu, Hashim Ghalib, Suman Rijal, Rosanna W. Peeling
Diagnosis of visceral leishmaniasisby Pankaj Srivastava, Anand Dayama, Sanjana Mehrotra, Shyam Sundar
Enteric fever diagnostics reviewsby Paula Bianca Blomquist
Mobile Phone Based Clinical Microscopy for Global Health Applicationsby David N. Breslauer, Robi N. Maamari, Neil A. Switz, Wilbur A. Lam, Daniel A. Fletcher
Web-Based Virtual Microscopy for Parasitology: A Novel Tool for Education and Quality Assuranceby Ewert Linder, Mikael Lundin, Cecilia Thors, Marianne Lebbad, Jadwiga Winiecka-Krusnell, Heikki Helin, Byron Leiva, Jorma Isola, Johan Lundin
Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysisby Freddie Bwanga, Sven Hoffner, Melles Haile, Moses L Joloba
Tuberculosis Diagnostic Technology Landscapeby David Boyle, Madhu Pai
Alternative methods of diagnosing drug resistance - What can they do for me?by David AJ Moore, N Sarita Shah
Point-of-Care Tests to Strengthen Health Systems and Save Newborn Lives: The Case of Syphilisby David Mabey, Kimberly Sollis, Helen Kelly, Adele Schwartz Benzaken, Edward Bitarakwate, John Changalucha, Xiang-Sheng Chen, Yue-Pin Ying, Patricia Garcia, Susan Strasser, Namwinga Chintu, Tikki Pang, Fern Terris-Prestholt, Sedona Sweeney, Rosanna Peeling
Diagnostic Accuracy of Molecular Amplification Tests for Human African Trypanosomiasis—Systematic Reviewby Claire M. Mugasa, Emily R. Adams, Kimberly R. Boer, Heleen C. Dyserinck, Philippe Büscher
Towards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisisby Enock Matovu, Anne Juliet Kazibwe, Claire Mack Mugasa, Joseph Mathu Ndungu, Zablon Kithingi
Nucleic acid amplification testing for Neisseria gonorrhoeae: an ongoing challengeby David M Whiley, John W Tapsall, Theo P Sloots
Indian Bacterial Surveillance Study Shows High Number of Resistant Bacteria - Article of the Month, June 2012by Editors
June’s article of the month features a paper from Infection and Drug Resistance called “High prevalence of extended-spectrum β-lactamase-producing pathogens: results of a surveillance study in two hospitals in Ujjain, India”.
Bug Challengeby Editors
Our first "Bug Challenge" comes from Mahosot Hospital, Vientiane, Laos
May's article of the month features a supplement from Clinical Infectious Diseases on "Pneumonia Etiology Research for Clinical Health"