This video seminar describes research to develop a low-cost, field-based test to detect several slow-clearing ACT drug compounds from unprocessed fingerstick blood samples
The European Mobile Laboratory, EMLab, was the first EBOV diagnostics unit deployed to the outbreak epicentre by WHO in March 2014.
Laboratory systems and diagnostic technologies are a critical pillar in the fight against malaria. The World Health Organization (WHO) recommends diagnostic testing for all people with suspected malaria before treatment is administered.
Uganda has shown particular success in its National Sample and Results Transport Network (NSRTN).
Call for Papers: Special issue on strengthening tuberculosis diagnostic networks in Africa - African Journal of Laboratory Medicine
From our colleagues at the African Society for Laboratory Medicine (ASLM) - The Role of Public Health Institutes in Achieving Public Health Goals
East African Leaders Join Together to Develop Country-Specific Plans for Point-of-Care Testing.
Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOEby Scott Ayton et al
Pioneering New Diagnostics: Addressing Challenges and Implications for Point-of-Care Testing in African Settingsby Laurel Oldach
Effects of introducing Xpert MTB/RIF test on multi-drug resistant tuberculosis diagnosis in KwaZulu-Natal South Africaby Nomonde R Dlamini-Mvelase, Lise Werner, Rogerio Phili, Lindiwe P Cele and Koleka P Mlisana
Rapid and Inexpensive Detection of MDR Mycobacterium tuberculosis using a Resazurin Microtitreplate Assay in a High Burden Tuberculosis Reference Laboratoryby Prenika Jaglal, Melendhran Pillay, Koleka Mlisana
The Clinical and Economic Impact of Point-of-Care CD4 Testing in Mozambique and Other Resource-Limited Settings: A Cost-Effectiveness Analysis.by Emily P. Hyle et al.
An Integrated Lab-on-Chip for Rapid Identification and Simultaneous Differentiation of Tropical Pathogensby Jeslin J. L. Tan, Monica Capozzoli, et al
Accurate reference values are essential for the correct interpretation of laboratory tests and clinical decision-making. Reference values should be established by testing a large number of healthy individuals. The results are then averaged and a range (plus or minus 2 standard deviations of the mean) of ‘normal’ values are established. The reference range of a test may be affected by the age and sex of the patient, and the variation is higher in some tests than in others. Because of this, reference values should be divided in groups according to age and gender, and ideally also according to ethnicity and geographical region.
Identification of Seroreactive Proteins of Leptospira interrogans Serovar Copenhageni Using a High-Density Protein Microarray Approachby Carolina Lessa-Aquino, Camila Borges Rodrigues, Jozelyn Pablo, Rie Sasaki, Algis Jasinskas, Li Liang, Elsio A. Wunder Jr, Guilherme S. Ribeiro, Adam Vigil, Ricardo Galler, Douglas Molina, Xiaowu Liang, Mitermayer G. Reis, Albert I. Ko, Marco Alberto Medeiros, Philip L. Felgner
Diagnostic Accuracy of Loopamp Trypanosoma brucei Detection Kit for Diagnosis of Human African Trypanosomiasis in Clinical Samplesby Patrick Mitashi, Epco Hasker, Dieudonne Mumba Ngoyi, Pati Patient Pyana, Veerle Lejon, Wim Van der Veken, Pascal Lutumba, Philippe Buscher, Marleen Boelaert, Stijn Deborggraeve
Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-Salmonella IgA in Secretions of Peripheral Blood in Lymphocytes in Patients in Dhaka, Bangladeshby Farhana Khanam, Alaullah Sheikh, Abu Sayeed, Saraur Bhuiyan, Feroza Kaneez Choudhury, Umme Salma, Shahnaz Pervin, Tania Sultana, Dilruba Ahmed, Doli Goswami, Lokman Hossain, KZ Mamun, Richell C Charles, W. Abdullah Brooks, Stephen B. Calderwood, Alejandro Cravioto, Edward T Ryan, Firdausi Qadri
The authors present the story of building a succesful research laboratory in Cameroon, including how they managed building up the infrastructure, equipment maintenance, staff training.
Development and Validation of a Novel Diagnostic Test for Human Brucellosis Using a Glyco-engineered Antigen Coupled to Magnetic Beadsby Andrés E. Ciocchini, Diego A. Rey Serantes, Luciano J. Melli, Jeremy A. Iwashkiw, Bettina Deodata, Jorge Wallach, Mario F. FEldman, Juan E. Ugalde, Diego J. Comerci
Leishmaniasis Direct Agglutination Test: Using Pictorials as Training Materials to REduce Inter-Reader Variability and Improve Accuracyby Emily R Adams, Diane Jacquet, Gerard Schoone, Kamlesh Gidwani, Marleern Boelaert, Jane Cunningham
Fantastic parasitology blog